London, September 1854. A terrifying outbreak of cholera has paralyzed the impoverished district of Soho. While the medical establishment blames the foul “miasma” in the air, Beatrice Vale, a gifted cartographer working in the shadow of a dismissive city surveyor, sees a different truth. By mapping the addresses of the dead, she discovers a chillingly perfect circle of death radiating from the Broad Street water pump. When she investigates, she meets Dr. Thomas Finch, a rogue physician who believes the disease is in the water. Together, they uncover a horrific conspiracy: the well wasn’t just contaminated by accident. A ruthless railway baron is deliberately poisoning the slum’s water supply to force terrified residents to abandon their homes, clearing the land for a lucrative new train line. Hunted through the fog-choked streets of London, Beatrice and Thomas must prove the water is a weapon before the entire district is eradicated.